CO2N: Let's Convert!.

This projects aims to building a Website to support individuals, families, companies and other organizations in the transition towards a CO2 neutral way of living and working/producing. To this end, the site will contain a footprint calculator for CO2 emissions as well as tools to provide users with tips, advices, donations and feedback. It will also be possible to certify if a company is CO2 neutral and allow them to use a logo/stamp that they can add to their products. This project is developed under the BlendED AIM framework and with a team of 7 students from all over Europe. (4 IT, 2 Design, 1 Marketing).<br /

Exercise induction of gut microbiota modifications in obese, non-obese and hypertensive rats

Background: Obesity is a multifactor disease associated with cardiovascular disorders such as hypertension. Recently, gut microbiota was linked to obesity pathogenesisand shown to influence the host metabolism. Moreover, several factors such as host-genotype and life-style have been shown to modulate gut microbiota composition. Exercise is a well-known agent used for the treatment of numerous pathologies, such as obesity and hypertension; it has recently been demonstrated to shape gut microbiota consortia. Since exercise-altered microbiota could possibly improve the treatment of diseases related to dysfunctional microbiota, this study aimed to examine the effect of controlled exercise training on gut microbial composition in Obese rats (n = 3), non-obese Wistar rats (n = 3) and Spontaneously Hypertensive rats (n = 3). Pyrosequencing of 16S rRNA genes from fecal samples collected before and after exercise training was used for this purpose. Results: Exercise altered the composition and diversity of gut bacteria at genus level in all rat lineages. Allobaculum (Hypertensive rats), Pseudomonas and Lactobacillus (Obese rats) were shown to be enriched after exercise, while Streptococcus (Wistar rats), Aggregatibacter and Sutturella (Hypertensive rats) were more enhanced before exercise. A significant correlation was seen in the Clostridiaceae and Bacteroidaceae families and Oscillospira and Ruminococcus genera with blood lactate accumulation. Moreover, Wistar and Hypertensive rats were shown to share a similar microbiota composition, as opposed to Obese rats. Finally, Streptococcus alactolyticus, Bifidobacterium animalis, Ruminococcus gnavus, Aggregatibacter pneumotropica and Bifidobacterium pseudolongum were enriched in Obese rats. Conclusions: These data indicate that non-obese and hypertensive rats harbor a different gut microbiota from obese rats and that exercise training alters gut microbiota from an obese and hypertensive genotype background

Matriz dérmica acelular para recobrimento radicular em recessão gengival unitária: relato de caso

Introduction: Gingival recession (GR) is defined as the apical migration of the gingival margin, resulting in root exposure in the oral environment, it is known that among its multifactorial etiology the use of orthodontic appliance is cited as a risk factor for GR in patients with a thin periodontal phenotype. Objective: This paper aims to report a case of single root coverage using acellular dermal matrix (MDA) graft. Case Report: Female patient, 24 years old, non-smoker and without systemic alterations, attended the dental clinic of a college in northern Brazil with the main complaint of dentin hypersensitivity in the posterosuperior region. The clinical examination showed stage I type 1 recession in tooth 25 associated with orthodontic movement in the buccolingual direction, the GR of tooth 15 had 2mm (cervico-apical direction) and 1mm (mesiodistal direction), it was also observed Thin scalloped phenotype, no interproximal bone loss, no bleeding on probing and dental biofilm. The indicated treatment was root coverage using the coronal slip technique with MDA fixed with sutures. Conclusion: Given the above, we verified that the clinical results reported in this study indicated a great clinical result with excellent predictability of success, increased keratinized mucosal band and clinical insertion gain.Introducción: La recesión gingival (RG) se define como la migración apical del margen gingival, resultando en exposición radicular en el ambiente oral, se sabe que entre su etiología multifactorial se cita el uso de aparato de ortodoncia como factor de riesgo para RG en pacientes con un fenotipo periodontal delgado. Objetivo: Este artículo tiene como objetivo reportar un caso de cobertura radicular única utilizando injerto de matriz dérmica acelular (MDA). Caso clínico: Paciente mujer, 24 años, no fumadora y sin alteraciones sistémicas, acudió a la consulta odontológica de una facultad del norte de Brasil con el principal síntoma de hipersensibilidad dentinaria en la región posterosuperior. El examen clínico mostró recesión en estadio I tipo 1 en el diente 25 asociado a movimiento ortodóncico en dirección vestibulolingual, el GR del diente 15 tenía 2 mm (dirección cérvico-apical) y 1 mm (dirección mesio-distal). Fenotipo festoneado fino, sin hueso interproximal pérdida, sin sangrado al sondaje y biofilm dental. El tratamiento indicado fue la cobertura radicular mediante la técnica de deslizamiento coronal con MDA fijado con suturas. Conclusión: Dado lo anterior, verificamos que los resultados clínicos reportados en este estudio indicaron un gran resultado clínico con excelente predictibilidad de éxito, aumento de la banda mucosa queratinizada y ganancia de inserción clínica.Introdução: A recessão gengival (RG) é definida como a migração apical da margem gengival, resultando na exposição radicular no meio bucal, sabe-se que dentre a sua etiologia multifatorial cita-se o uso de aparelho ortodôntico como um fator de risco para RG em pacientes com fenótipo periodontal delgado. Objetivo: O presente trabalho tem como objetivo relatar um caso de recobrimento radicular unitário utilizando enxerto de matriz dérmica acelular (MDA). Relato de Caso: Paciente sexo feminino, 24 anos, não fumante e sem alterações sistêmicas, compareceu a clínica odontológica de uma faculdade no norte do Brasil com a queixa principal de hipersensibilidade dentinária na região pôstero-superior. No exame clínico verificou-se estágio I recessão tipo 1 no dente 25 associada a movimentação ortodôntica no sentido vestíbulo-lingual, a RG do dente 15 apresentava 2mm (sentido cérvico-apical) e 1mm (sentido mésio-distal), observou-se ainda fenótipo fino festonado, sem perdas ósseas interproximais, ausência de sangramento a sondagem e biofilme dentário. O tratamento indicado foi o recobrimento radicular pela técnica de deslize coronal com MDA fixada com suturas. Conclusão: Diante do exposto, verificamos que os resultados clínicos relatados neste trabalho indicaram um ótimo resultado clínico e com ótima previsibilidade de sucesso, aumento da faixa de mucosa queratinizada e ganho clínico de inserção

Measurement of the cosmic ray spectrum above 4×10184{\times}10^{18} eV using inclined events detected with the Pierre Auger Observatory

A measurement of the cosmic-ray spectrum for energies exceeding $4{\times}10^{18}$ eV is presented, which is based on the analysis of showers with zenith angles greater than $60^{\circ}$ detected with the Pierre Auger Observatory between 1 January 2004 and 31 December 2013. The measured spectrum confirms a flux suppression at the highest energies. Above $5.3{\times}10^{18}$ eV, the "ankle", the flux can be described by a power law $E^{-\gamma}$ with index $\gamma=2.70 \pm 0.02 \,\text{(stat)} \pm 0.1\,\text{(sys)}$ followed by a smooth suppression region. For the energy ($E_\text{s}$) at which the spectral flux has fallen to one-half of its extrapolated value in the absence of suppression, we find $E_\text{s}=(5.12\pm0.25\,\text{(stat)}^{+1.0}_{-1.2}\,\text{(sys)}){\times}10^{19}$ eV.Comment: Replaced with published version. Added journal reference and DO

Desenvolvimento neuropsicomotor na infância e eventos obstétricos

Objective: Investigate and analyze the relationship between obstetric events and neuropsychomotor development in children aged 0 to 12 years. The research aims to contribute to understanding the impacts of these events on child development, providing insights that can guide obstetric practices, early interventions, and strategies for promoting health in childhood.Introduction: Contextualization and relevance of the study, addressing the importance of understanding the influence of obstetric events on neuropsychomotor child development. The need to explore this relationship is emphasized to inform obstetric practices and intervention strategies that promote healthy development in childhood. Methodology: Searches were conducted in the PubMed, Scielo, and Latindex databases using terms related to neuropsychomotor development and obstetric events. The DeCS terms used included "Neurology," "Growth and Development," "Child Development," "Obstetric Delivery," "Child Psychiatry," and "Adverse Birth Outcomes," combined with boolean operators AND and OR. Conclusion: The conclusion highlights the relationship between obstetric events and neuropsychomotor development. Understanding risk factors guides prevention and personalized interventions, addressing neonatal vulnerability. Evaluation and diagnosis are vital for adapted support, and therapeutic interventions drive progress. Emphasis on prevention, family support, research, and advocacy is crucial for inclusive environments and healthy development.Objetivo: Investigar e analisar a relação entre eventos obstétricos e o desenvolvimento neuropsicomotor em crianças de 0 a 12 anos. A pesquisa visa contribuir para a compreensão dos impactos desses eventos no desenvolvimento infantil, fornecendo insights que possam orientar práticas obstétricas, intervenções precoces e estratégias de promoção da saúde na infância. Introdução: Contextualização e relevância do estudo, abordando a importância de compreender a influência dos eventos obstétricos no desenvolvimento neuropsicomotor infantil. Destaca-se a necessidade de explorar essa relação para informar práticas obstétricas e estratégias de intervenção que promovam um desenvolvimento saudável na infância. Metodologia: Foram conduzidas buscas nas bases de dados PubMed, Scielo e Latindex usando termos relacionados ao desenvolvimento neuropsicomotor e eventos obstétricos. Os DeCs utilizados incluíram "Neurologia", "Crescimento e Desenvolvimento", "Desenvolvimento Infantil", "Parto Obstétrico", "Psiquiatria Infantil" e "Desfechos Adversos do Nascimento", combinados por operadores booleanos AND e OR. Conclusão: A conclusão destaca a relação entre eventos obstétricos e desenvolvimento neuropsicomotor. Entender fatores de risco guia prevenção e intervenções personalizadas, atendendo à vulnerabilidade neonatal. Avaliação e diagnóstico são vitais para suporte adaptado, e intervenções terapêuticas impulsionam o progresso. A ênfase em prevenção, suporte familiar, pesquisa e advocacia é crucial para ambientes inclusivos e o desenvolvimento saudável

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio